The AFP (Agence France Presse) reports that Senator Gregg of New Hampshire is President Obama's leading choice for Secretary of Commerce. (You might recall that the President's first choice, Governor Richardson of New Mexico, withdrew.) Senator Gregg is a solid conservative, and his appointment would signal that the President is serious about reaching across the aisle. Moreover, the appointment of someone with the gravitas and intellect of Senator Gregg would also signal a larger role of the Department of Commerce that the Department has had in prior administrations.
http://www.google.com/hostednews/afp/article/ALeqM5gVBeA2BLjrnA8hfmXNCVzk2KZDvw
Note, however, that the appointment of Senator Gregg would leave a senate seat vacant, and the Democratic Governor of New Hampshire would be entitled to appoint Senator Gregg's successor pending the 2010 election.